RAF Typhoon FGR4s have operated alongside France's air force in a combined operation against an subterranean weapons facility in Syria operated by the IS group, according to the UK Ministry of Defence.
The location, pinpointed through surveillance, was thought to be containing munitions and bombs, the release indicated, and was situated in mountains just north of Palmyra in Syria's central region.
"Our fighter planes employed Paveway IV guided bombs to hit a number of approach shafts providing entry to the depot... initial indications indicate the objective was successfully hit," officials stated.
There was no indication of any civilian impact in the attack late on Saturday and each participating jet returned to base without incident, the MoD added.
The Typhoon FGR4s were supported by a Voyager refuelling tanker.
The Islamic State group - also known as ISIS - imposed extremist governance over large swathes of Syria and Iraq prior to its 2019 collapse.
"This operation demonstrates our UK leadership, and commitment to work closely with our allies, to stamp out any re-emergence of the terrorist group and their dangerous and violent ideologies in the region," UK Defence Secretary John Healey stated.
RAF aircraft have carried out surveillance missions over Syrian airspace to "deter any efforts to regroup" of Islamic State after its routing at the Baghuz confrontation in 2019, the ministry said.
"I want to thank the personnel of British forces who took part in this operation for their expertise and their valour," the Defence Secretary said. "They were part of numerous British troops deployed over the holidays. This operation, to eliminate militants who threaten our safety, highlights how our armed forces are ready to step up, throughout the year, keeping Britain secure at home and powerful internationally."
During December, the United States armed forces carried out what it described as a "massive strike" targeting Daesh sites in the country, following an ambush killed two US troops and a civilian interpreter in Palmyra.
The U.N. estimates IS still boasts between 5,000 and 7,000 fighters in both countries.
